Vitiligo

Vitiligo – the most common among gipomelanozov disease. Characterized by the appearance of depigmentation of the skin lesions. In their microscopic examination revealed the absence or reduction pigment – melanin. Its prevalence is 1-2% of the total world population. In Russia, due to poor nutrition, environmental problems and systematic nerve stress, the share 3-4% or 4-5 million people. The majority of dermatologists in Russia believed that vitiligo is not treated. Such is the situation today with vitiligo in Russia.

What do those who first encountered this disease who are struggling every day with him? What in the world? The volume of research capacity and funding towards the world's leading pharmaceutical laboratories to develop effective treatments for Vitiligo for the past 30 years, grew up in times and continues to grow. With regard to research on vitiligo, they are conducted in many countries. In Russia, unfortunately, such studies so far are not enough. Today in the world science on the issue of vitiligo can say the following. Work aimed at creating artificially synthesized drug that cured the patient of vitiligo "once and for all" were considered ineffective.

Or, in Anyway, they decided to postpone. Such a decision influenced by many factors. But the main acknowledged the fact, that among the experts still disagree about the causes of the disease. However, the experience acquired already in Russia in recent years shows that not less than 70% of the main provoking factor of disease is stress. More promising were found in drug development, where the active ingredient used plant extracts or created on the basis of their organic compounds.


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Herbs

But for some herbs will not live I can tell you. Now let's see how many calories in proteins containing fats and carbohydrates – and then immediately answer in proteins 4 kcal in carbohydrate and 4 calories, but in as much fat as much as 9 kcal. But this does not mean that if we drink 500 grams of vegetable oil per day that we get the number of calories that we need on the day. Proteins, fats and carbohydrates needed unites in its ration in proportion. What does this mean? Let us examine an example of proteins: The average person in 1 kg of their weight should eat between 0.7 and 1.7 grams of protein per day, the range depends on the kind of occupation, age, disease. For example those people who bodybuilding, bodybuilding and strength training – you need to eat about 2-3.5 grams of protein per 1 kg per day, and some professionals use, and about 4-5 grams of protein. And where they take this amount of protein per day? For example vozmem profesionala athlete who weighs 120 kg and 4.5 g protein upotrebyaet 1 kg of its weight, so how can he be eating a? It turns out that he needs to eating a nearly 3 kg of beef per day! And that's just the protein, and in order to 'To drag iron' it still needs energy, but it + more carbohydrates and fat! For this they use energy drinks, protein powders, but that's another story. Many believe that in order to lose weight – no need to eat fats, but kakraz on the contrary – there are fat can not eat a lot of carbohydrates! (And better not to eat and exercise).

Why so raskazyvat will not for a long time and the article is not about that. So eating a little better with a cutlet Boiled potatoes than good sardelyu with pasta and bread. And now let us count the approximate number of calories in the same salad with new potatoes mackerel: Ingredients: – 150 g green peas pods 60 calories – 500 g young potatoes 350 calories – 350 g smoked mackerel 1050 calories – 250 g cherry tomatoes Kkkal 30 – 1 head lettuce 35 calories Total: 1525 calories, so a salad accommodates 6 people, we get about 280 calories. This means that such a salad, we will be able to fully eat for breakfast, and drink his cup of kofe:)


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Catheterization

In this situation, we must carefully change the location of the catheter, pull it toward you, and to make follow-HS volume of circulating fluid. During the operation it is necessary to closely monitor the patient (subjective feeling, heart rate, blood pressure, BH skin condition, behavior). If you experience any complications (fever, hypotension, bleeding, etc.) to try to remove them without stopping the HS. Along with heparin in arterial line during HS infusion administered at a dose of 1.5-2.0 trental mg / kg in 500 ml of saline solution, and if necessary being symptomatic therapy. We should not make attempts rastrombirovaniya sorbent during HS saline as possible hemolysis. Silicone and PVC line is not recommended needle. Injections should be made through a special lock or a rubber segment. With some experience in the operation hemosorption easy to implement and is safe for the patient.

High biocompatibility biospecific sorbents virtually eliminates complications associated with connecting the extracorporeal circuit with a sorbent to vascular system of the patient. Reduced to a minimum the possibility of anafilaticheskih reactions, pulmonary edema, metabolic disorders, which are described for a number of dialysis membranes and some natural sorbents first generation. Complications of HS using a sorbent of this type can be associated mainly with the technique or methodological errors of the operation. 1. Complications due to technical errors: o defects in the catheterization of central and peripheral blood vessels; o depressurization perfusion system that untimely identification can cause significant blood loss; o occurrence air embolism in displacement of blood from massoobmennika air, in the process itself is a complication of HS may occur during veno-venous connection option when silicone tube slips out from under the roller pump, or lack of proper supervision by medical staff during the displacement of blood with air; o the risk of infection in patients with non-compliance with GS rules of asepsis and antisepsis. 2.

Complications associated with inadequacy of the methodology of the GS: o chills – the most frequent and quite serious complication of HS. Chills associated with pyrogenic reactions due to poor cleaning of the sorbent or pyrogenicity transfuznyh environments, rather easily cropped. There is also evidence of the role of large doses of heparin in the occurrence of this complication. Massive lipolysis induced by heparin superdozami, leading to consumption of calcium may be the reason for this; o collaptoid reaction – a common cause of this complication is hypovolemia and circulatory centralization. Sorption of vasoactive peptides with pressor leads to decentralization and circulatory hypotension; o massoobmennika thrombosis and extracorporeal systems are most commonly associated with the difficulty of correcting the system of regulation the state of aggregation of blood when not in use opportunities to influence the components of this complex system and for the prevention of thrombotic events only apply large doses of heparin. It should also be noted that it was in septic disease is sharply reduced primary target of action of heparin – antithrombin-III. So large doses of heparin does not facilitate the perfusion, but rather the contrary, contribute to the development of adverse reactions of heparin.


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